منابع مشابه
Relation Between RNA Sequences, Structures, and Shapes via Variation Networks
Background: RNA plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. RNA secondary structure represents various significant portions of RNA tertiary structure. Since the biological function of RNA is concluded indirectly from its primary structure, it would be important to analyze the relations between the RNA sequences and t...
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Background: RNA molecules play many important regulatory, catalytic and structural <span style="font-variant: normal; font-style: norma...
متن کاملrelation between rna sequences, structures, and shapes via variation networks
background: rna plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. rna secondary structure represents various significant portions of rna tertiary structure. since the biological function of rna is concluded indirectly from its primary structure, it would be important to analyze the relations between the rna sequences and t...
متن کاملClassifying RNA pseudoknotted structures
Computational prediction of the minimum free energy (mfe) secondary structure of an RNA molecule from its base sequence is valuable in understanding the structure and function of the molecule. Since the general problem of predicting pseudoknotted secondary structures is NP-hard, several algorithms have been proposed that find the mfe secondary structure from a restricted class of secondary stru...
متن کاملIrreducibility in RNA structures.
In this paper, we study irreducibility in RNA structures. By RNA structure, we mean RNA secondary as well as RNA pseudoknot structures as abstract contact structures. We give an analysis contrasting random and minimum free energy (mfe) configurations and secondary versus pseudoknots structures. In the process, we compute various distributions: the numbers of irreducible substructures and their ...
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ژورنال
عنوان ژورنال: Nature Methods
سال: 2011
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.1826